New PDF release: Chemistry and Molecular Aspects of Drug Design and Action

By E. A. Rekka,P. N. Kourounakis

An ever-increasing call for for greater medications, increased defense criteria, and monetary concerns have all resulted in a dramatic paradigm shift within the approach that medications are being came across and built. referred to as rational drug layout, this modern approach is outlined by means of 3 major steps: the invention of lead compounds, surgical manipulation to boost pharmacophores, and extra optimization to supply the simplest compounds.

Chemistry and Molecular points of Drug layout and Action brings jointly a powerful choice of world-renowned pharmacochemistry scientists who're at present defining the emergence of rational drug layout. providing perception from their very own really good examine, those pioneers spotlight the range of ways being hired during this box, together with those who begin by means of contemplating both molecular mechanisms of drug motion, or the metabolizing enzyme motion happening within the constitution of a drug molecule. one other procedure they discover is person who starts off from the pathobiochemistry and pathophysiology of goal ailments. in addition, the booklet additionally considers drug improvement that uses already constructed compounds saved in facts banks.

Divided into 5 components, each one devoted to numerous facets of the classical medicinal chemistry technique, the textual content makes it effortless for readers to target a box of particular curiosity.

  • Chemical, Biochemical, and organic points of Pathophysiological Conditions
  • Classical Medicinal Chemistry
  • Drug layout, Chemical and Molecular features of Drug Action
  • Drug Xenobiotic Metabolism
  • Physical natural and Theoretical Medicinal Chemistry
  • While every one part could be studied independently, the mixed fabric during this quantity presents the main accomplished evaluate to be had on rational drug layout. This paintings is a useful source either for these coming into the sphere, in addition to these researchers seeking to construct on present progress.

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    Chemistry and Molecular Aspects of Drug Design and Action by E. A. Rekka,P. N. Kourounakis

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